Fresh concerns raised over controversial ‘three parent baby’ therapy which aims to eliminate inherited disease

Jul 7, 2016 by Jill

from bt.com:

The controversial technique was approved by Parliament last year.

Hidden effects on metabolism and ageing may make it harder to rid future generations of devastating inherited diseases using a controversial “three parent baby” treatment, new research suggests.

Scientists working with mice found that an early mismatch of DNA had disturbing consequences later in life, including accelerated ageing.

Whether humans might respond the same way is not yet known. But the research raises new concerns about attempts to eliminate inherited disease by replacing defective mitochondrial DNA.

Last year Parliament took the bold step of approving mitochondrial replacement therapy, which would allow DNA in human embryos to be altered in a way that affects future generations.

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